The world is infected with a rare virus of Martian origin, which causes those infected with it to morph into strange creatures whose sole purpose is to infect more people and kill those immune to the infection. Misa Stanley is a nurse working on the front lines when infected patients start morphing into creatures. Misa must manage to save herself and her two siblings from the creatures as they all exhibit signs of immunity to the virus. Even after escaping the infection zone, the struggle isn't over because world leaders announce that in exactly 12 months, infection will have wiped out 80% of Earth's human and animal population. In order to preserve the species, the US government offered sanctuary in cryogenic stasis at a secret base in Yosemite national park. As the three make their way to the cryo facility, they meet a young soldier named Rebecca who falls in love with Misa. Dare the two fall in love or will that proved to be a fatal mistake.