The eccentric Shin Soru and slightly popular Mitsuha Reika were both students of Class 1-A at Itami High School. Seatmates at first, their fates began to intertwine when both of them were mysteriously teleported to another world by a strange pillar of light.

Upon their arrival, they were welcomed by the harsh nature of this parallel world. However, both of them managed to survive thanks to Soru's mysterious power, which he already possessed before their arrival on the other world. With a single thought, he can shift anything his eyes have laid upon! That power of his was soon uncovered by others, whom they dubbed "Shift."

With Soru's ability and Reika's adaptability, they ventured into this new world together. Although their personalities didn't match well, they discovered places that seemed unreal, met new people and friends, and awakened their innermost emotions, which they thought wouldn't happen.