As inconceivable as it may sound, Marge is indeed a boy. And Marge is his legal name. Not by choice.
After this horrifying and scarring mistake made by his parents, Marge finds himself cut off from his family and at Carolton University. Thankfully, everyone there is completely normal. Except for maybe Hlurga, the Lovecraftian monster. Or Jane, the robot. Or Jackie, a yaoi fangirl.
Either way, he's there, doing college stuff, like the champ he is.