A vampire named Shizu, is a part of a species of vampires that can shapeshift into other people after devouring their life energy. These vampires are known as "Body Stealers". After his dearest friend, Nao dies from a vampire hunter attack, Shizu decides to use his powers to transform into his friend, so their souls could become one. Then, after years of being in hiding, a government agency finds out about Shizu, and forcefully enrolls him in a school specifically for vampires. The two scientists, Cleo and Yuki claim that they want to find a cure for the Body Stealers so to stop their cravings for human energy. But with the school being located on a remote island, would this be a good opportunity for him to get cured or will it become more like a prison that he'll fight to break free from? Well, the latter is chosen, and Shizu, along with his group of friends, Kilu, Reira, Nero and Iris, form the "Vampire Break-Out Club".